Vagus nerve stimulation (VNS) has emerged as a leading non-invasive solution for managing stress, anxiety, depression, and even chronic inflammation. With growing scientific support and consumer interest, several innovative VNS devices have entered the UK market in recent years. This 2025 comparison guide explores the best vagus nerve stimulation devices in the UK, providing a comprehensive breakdown of top-rated products, key features, and what sets each device apart.
1. Pulsetto – The Top Choice in the UK (2025)
Pulsetto leads the UK market in 2025 with its clinically backed, user-centric vagus nerve stimulation device. Designed in collaboration with healthcare professionals and neurologists, Pulsetto uses transcutaneous electrical nerve stimulation (TENS) technology to gently activate the vagus nerve through the skin, delivering results without side effects.
Key Features:
- Non-invasive & drug-free: Offers a safe alternative to medication.
- Bluetooth-enabled: Syncs with an intuitive mobile app to personalise sessions.
- Multiple therapy modes: Tailored programs for stress relief, sleep support, anxiety, and chronic pain.
- Portable & sleek design: Ideal for at-home or on-the-go use.
Pulsetto’s ongoing commitment to innovation, paired with outstanding customer support and scientifically validated results, makes it the standout choice for UK users looking for reliable vagus nerve stimulation in 2025.
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2. gammaCore Sapphire™
gammaCore Sapphire™, developed by electroCore, is a handheld VNS device often used under medical supervision. While traditionally marketed for cluster headaches and migraines, it’s also gaining recognition in mental wellness communities.
Key Features:
- Clinically approved for headache treatment.
- Non-invasive cervical VNS technology.
- Used in both NHS and private clinics across the UK.
- Prescription may be required.
gammaCore is best suited for those with specific neurological conditions but remains an effective option for targeted VNS therapy.
3. Neuvana Xen
Neuvana’s Xen earbud device brings together neuroscience and audio technology by stimulating the vagus nerve through the ear canal. Connected to a smartphone, it plays calming music while delivering VNS, appealing particularly to younger audiences and biohackers.
Key Features:
- Music-based stimulation experience.
- Customisable intensity and session duration.
- Earbud-based delivery system.
- iOS and Android app integration.
While not medically certified in the UK, Neuvana offers a unique sensory approach to VNS and is often used as a wellness tool rather than a therapeutic device.
4. NuroKor mitouch
Primarily marketed for pain relief and physical recovery, the NuroKor mitouch also features a vagus nerve stimulation setting. The device uses bioelectrical therapy, including NMS (neuromuscular stimulation) and MC2 (microcurrent), with some compatibility for vagal activation.
Key Features:
- Multi-mode bioelectrical stimulation.
- Touchscreen interface.
- Suitable for muscle recovery and inflammation.
- Less focused on mental health applications.
NuroKor is an ideal crossover device for users interested in both nerve and muscle health, though it may lack the specificity found in dedicated VNS products.
5. Sensate 2
Sensate 2 is a pebble-shaped wearable that rests on the chest and uses infrasonic vibrations to stimulate the vagus nerve. While it does not use traditional electrical pulses, it is designed to calm the nervous system through resonance and breathing exercises.
Key Features:
- Infrasonic resonance-based technology.
- App-guided meditative sessions.
- Lightweight and travel-friendly.
- Strong emphasis on mindfulness and breathwork.
Although less clinical in nature, Sensate is widely praised in wellness circles for its calming effects and ease of use.
Final Thoughts
In 2025, consumers in the UK have an impressive array of Best vagus nerve stimulation devices in the UK to choose from, catering to various needs — from clinically approved treatments to wellness-focused innovations. For those seeking the most effective, versatile, and scientifically supported solution, Pulsetto remains the top recommendation.
